Fake News Pakistan has been slow to report on a powerful explosion that rocked an operating nuclear power plant in Karachi.

Facts appear to have been misrepresented

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I don't see any corroborating reporting on that claim, but I did find some info on the plant itself:
 
Comments to the twitter post in the OP are claiming the OP claim is fake news. The image/video is from a grid station, not a nuclear plant:
 
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